https://ogma.newcastle.edu.au/vital/access/ /manager/Index ${session.getAttribute("locale")} 5 P450 Oxidoreductase Deficiency: A Systematic Review and Meta-analysis of Genotypes, Phenotypes, and Their Relationships https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:49798 Wed 31 May 2023 15:38:53 AEST ]]> The effect of patient-managed stress dosing on electrolytes and blood pressure in acute illness in children with adrenal insufficiency https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:42671 Wed 31 Aug 2022 16:25:18 AEST ]]> Dietary intake and eating patterns of young children with type 1 diabetes achieving glycemic targets https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:35468 0.05). HbA1c was significantly higher in children offered food in a grazing pattern compared with those offered regular meals (mean 61 mmol/mol vs 43 mmol/mol (7.7% vs 6.1%), p=0.01). Conclusions: Dietary quality is a concern in young children with T1D with excessive saturated fat and inadequate vegetable intake. Our results suggest that young children meeting glycemic targets give insulin before meals and follow a routine eating pattern.]]> Wed 24 Nov 2021 15:51:19 AEDT ]]> Initiation of insulin pump therapy in children at diagnosis of type 1 diabetes resulted in improved long-term glycemic control https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:30972 Wed 19 Jan 2022 15:16:05 AEDT ]]> Bubble formation occurs in insulin pumps in response to changes in ambient temperature and atmospheric pressure but not as a result of vibration https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:19552 Wed 11 Apr 2018 17:20:54 AEST ]]> Extended insulin boluses cannot control postprandial glycemia as well as a standard bolus in children and adults using insulin pump therapy. https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:19521 Wed 11 Apr 2018 10:38:42 AEST ]]> Additional Insulin Is Required in Both the Early and Late Postprandial Periods for Meals High in Protein and Fat: A Randomized Trial https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:49023 Wed 03 May 2023 12:38:05 AEST ]]> Macronutrient Intake in Children and Adolescents with Type 1 Diabetes and Its Association with Glycemic Outcomes https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:54433 Tue 27 Feb 2024 14:05:42 AEDT ]]> Insulin strategies for dietary fat and protein in type 1 diabetes: A systematic review https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:49963 Tue 20 Jun 2023 14:36:29 AEST ]]> Healthy weight and overweight adolescents with type 1 diabetes mellitus do not meet recommendations for daily physical activity and sleep https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:54313 Tue 20 Feb 2024 14:29:22 AEDT ]]> Control Limitations in Models of T1DM and the Robustness of Optimal Insulin Delivery https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:43119 Tue 13 Sep 2022 14:32:31 AEST ]]> Late Afternoon Vigorous Exercise Increases Postmeal but Not Overnight Hypoglycemia in Adults with Type 1 Diabetes Managed with Automated Insulin Delivery https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:51324 1 week. The closed-loop set-point was temporarily increased 2 h pre-exercise and a snack eaten if plasma glucose was ≤126 mg/dL pre-exercise. Exercise commenced at ∼16:00. A standardized meal was eaten at ∼20:40. Hypoglycemic events were defined as a continuous glucose monitor (CGM) reading <70 mg/dL for ≥15 min. Four-hour postevening meal and overnight (00:00-06:00) CGM metrics for exercise were compared with the prior nonexercise day. Results: There was no severe hypoglycemia. Between 00:00 and 06:00, the proportion of nights with hypoglycemia did not differ postexercise versus control for HIE (18% vs. 11%; P = 0.688), RE (4% vs. 14%; P = 0.375), and MIE (7% vs. 14%; P = 0.625). Time in range (TIR) (70-180 mg/dL), >75% for all nights, did not differ between exercise conditions and control. Hypoglycemia episodes postmeal after exercise versus control did not differ for HIE (22% vs. 7%; P = 0.219) and MIE (10% vs. 14%; P > 0.999), but were greater post-RE (39% vs. 10%; P = 0.012). Conclusions: Overnight TIR was excellent with AID without increased hypoglycemia postexercise between 00:00 and 06:00 compared with nonexercise days. In contrast, hypoglycemia risk was increased after the first meal post-RE, suggesting the importance of greater vigilance and specific guidelines for meal-time dosing, particularly with vigorous RE. ACTRN12618000905268.]]> Thu 31 Aug 2023 14:35:00 AEST ]]> Adolescents with type 1 diabetes can achieve glycemic targets on intensive insulin therapy without excessive weight gain https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:51868 75 mmol/mol (>9.0%) in 2004 (p = .873), 2010 (p = .10) or 2016 (p = .630). Mean HbA1c decreased from 2004 to 2016 in the 10-13 year (69 mmol/mol (8.4%) vs. 57 mmol/mol (7.4%), p = <.001) and 14-17 year group (72 mmol/mol (8.7%) vs. 63 mmol/mol (7.9%), p = <.001). Prior to the implementation of MDI and CSII in 2004 only 10% of 10-13 year olds and 8% of 14-17 year olds achieved the international target for glycemic control (HbA1c 53 mmol/mol [<7.0%]). In 2016, this increased to 31% of 10-13 year olds and 21% of 14-17 year olds. CONCLUSIONS: BMI-SDS did not increase with the change to intensive insulin therapy despite a doubling in the number of adolescents achieving the recommended glycemic target of <7.0% (53 mmol/mol). HbA1c was not associated with weight gain.]]> Thu 21 Sep 2023 10:24:57 AEST ]]> In children and young people with type 1 diabetes using Pump therapy, an additional 40% of the insulin dose for a high-fat, high-protein breakfast improves postprandial glycaemic excursions: A cross-over trial https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:49335 Thu 11 May 2023 15:21:16 AEST ]]> For a high fat, high protein breakfast, preprandial administration of 125% of the insulin dose improves postprandial glycaemic excursions in people with type 1 diabetes using multiple daily injections: A cross-over trial https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:49334 Thu 11 May 2023 15:21:15 AEST ]]> Phenotype-genotype correlations in a series of Wolfram syndrome families https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:1443 Sat 24 Mar 2018 08:28:07 AEDT ]]> A diabetes awareness campaign prevents diabetic ketoacidosis in children at their initial presentation with type 1 diabetes https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:21443 Sat 24 Mar 2018 08:05:43 AEDT ]]> Performance limitations arising in closed loop control of blood glucose in type 1 diabetes https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:19441 Sat 24 Mar 2018 08:02:26 AEDT ]]> Nonlinear insulin to carbohydrate rule for treatment of type 1 diabetes https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:25372 Sat 24 Mar 2018 07:39:06 AEDT ]]> A performance limitation for blood glucose regulation in type 1 diabetes accounting for insulin delivery delays https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:29239 Sat 24 Mar 2018 07:36:52 AEDT ]]> Effectiveness of a predictive algorithm in the prevention of exercise-induced hypoglycemia in type 1 diabetes https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:29188 Sat 24 Mar 2018 07:31:38 AEDT ]]> Application of MPC incorporating stochastic programming to type 1 diabetes treatment https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:28535 Sat 24 Mar 2018 07:28:48 AEDT ]]> Influence of and optimal insulin therapy for a low-glycemic index meal in children with type 1 diabetes receiving intensive insulin therapy https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:4621 Sat 24 Mar 2018 07:21:53 AEDT ]]> Complex regulatory interactions control CRH gene expression https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:3174 Sat 24 Mar 2018 07:18:13 AEDT ]]> Advances in understanding corticotrophin-releasing hormone gene expression https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:3171 Sat 24 Mar 2018 07:18:12 AEDT ]]> The relationship between carbohydrate and the mealtime insulin dose in type 1 diabetes https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:22661 Sat 24 Mar 2018 07:15:39 AEDT ]]> A fundamental control limitation for linear positive systems with application to Type 1 diabetes treatment https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:24264 Sat 24 Mar 2018 07:14:57 AEDT ]]> Both dietary protein and fat increase postprandial glucose excursions in children with type 1 diabetes, and the effect is additive https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:23691 Sat 24 Mar 2018 07:13:26 AEDT ]]> Effects of Dietary Fat and Protein on Glucoregulatory Hormones in Adolescents and Young Adults with Type 1 Diabetes https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:44787 Mon 24 Oct 2022 09:17:37 AEDT ]]> The relationship between meal carbohydrate quantity and the insulin to carbohydrate ratio required to maintain glycaemia is non-linear in young people with type 1 diabetes: A randomized crossover trial https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:44790 Mon 24 Oct 2022 09:17:35 AEDT ]]> Families' reports of problematic foods, management strategies and continuous glucose monitoring in type 1 diabetes: A cross‐sectional study https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:49565 Mon 22 May 2023 09:20:15 AEST ]]> A systematic stochastic design strategy achieving an optimal tradeoff between peak BGL and probability of hypoglycaemic events for individuals having type 1 diabetes mellitus https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:36297 Mon 15 Apr 2024 10:40:44 AEST ]]> Temporal trends in diabetic ketoacidosis at diagnosis of paediatric type 1 diabetes between 2006 and 2016: results from 13 countries in three continents https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:44181 Mon 10 Oct 2022 10:48:25 AEDT ]]> Variations in the management of acute illness in children with congenital adrenal hyperplasia: an audit of three paediatric hospitals https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:33673 Mon 02 Dec 2019 14:46:09 AEDT ]]> Does dietary fat cause a dose dependent glycemic response in youth with type 1 diabetes? https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:48914 Fri 14 Apr 2023 18:21:18 AEST ]]>